Tumour heterogeneity poses a significant challenge to cancer biomarker research

BACKGROUND: The high degree of genomic diversity in cancer represents a challenge for identifying objective prognostic markers. We aimed to examine the extent of tumour heterogeneity and its effect on the evaluation of a selected prognostic marker using prostate cancer as a model. METHODS: We assess...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Cyll, Karolina, Ersvær, Elin, Vlatkovic, Ljiljana, Pradhan, Manohar, Kildal, Wanja, Avranden Kjær, Marte, Kleppe, Andreas, Hveem, Tarjei S, Carlsen, Birgitte, Gill, Silje, Löffeler, Sven, Haug, Erik Skaaheim, Wæhre, Håkon, Sooriakumaran, Prasanna, Danielsen, Håvard E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537489/
https://ncbi.nlm.nih.gov/pubmed/28618431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.171
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