The genomic dynamics during progression of lung adenocarcinomas

Intra-tumor heterogeneity is a big barrier to precision medicine. To explore the underlying clonal diversity in lung adenocarcinomas, we selected nine individuals with whole-genome sequencing data from primary and matched metastatic tumors as a cohort for study. Similar global pattern of arm-level c...

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Dades bibliogràfiques
Publicat a:J Hum Genet
Autors principals: Yang, Bin, Luo, Longhai, Luo, Wen, Zhou, Yong, Yang, Chao, Xiong, Teng, Li, Xiangchun, Meng, Xuan, Li, Lin, Zhang, Xiaopin, Wang, Zhe, Wang, Zhixin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537414/
https://ncbi.nlm.nih.gov/pubmed/28381877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2017.40
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