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Inhibition of SV40 replicon function by engineered antisense RNA transcribed by RNA polymerase III.
Promoters recognized by RNA polymerase III were used to direct synthesis of RNAs of opposite polarity to the 5' end of the mRNA for the large T-antigen of SV40. A construct was made utilizing the adenovirus (human type II) VA1 gene promoter linked to 163 bp of SV40 DNA sequences cloned in antis...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1987
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC553741/ https://ncbi.nlm.nih.gov/pubmed/2446865 |
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