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A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii

Antimicrobial peptides (AMPs) represent a promising therapeutic alternative for the treatment of antibiotic-resistant bacterial infections. The present study investigates the antimicrobial activity of new, rationally-designed derivatives of a short α-helical peptide, RR. From the peptides designed,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mohamed, Mohamed F., Brezden, Anna, Mohammad, Haroon, Chmielewski, Jean, Seleem, Mohamed N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537347/
https://ncbi.nlm.nih.gov/pubmed/28761101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07440-0
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