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Immune selection during tumor checkpoint inhibition therapy paves way for NK-cell “missing self” recognition

The ability of NK cells to specifically recognize cells lacking expression of self-MHC class I molecules was discovered over 30 years ago. It provided the foundation for the “missing self” hypothesis. Research in the two past decades has contributed to a detailed understanding of the molecular mecha...

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Bibliografische gegevens
Gepubliceerd in:Immunogenetics
Hoofdauteurs: Malmberg, Karl-Johan, Sohlberg, Ebba, Goodridge, Jodie P., Ljunggren, Hans-Gustaf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537320/
https://ncbi.nlm.nih.gov/pubmed/28699110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-017-1011-9
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