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Immune selection during tumor checkpoint inhibition therapy paves way for NK-cell “missing self” recognition
The ability of NK cells to specifically recognize cells lacking expression of self-MHC class I molecules was discovered over 30 years ago. It provided the foundation for the “missing self” hypothesis. Research in the two past decades has contributed to a detailed understanding of the molecular mecha...
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| Veröffentlicht in: | Immunogenetics |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5537320/ https://ncbi.nlm.nih.gov/pubmed/28699110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-017-1011-9 |
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