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Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heart
The clinical use of doxorubicin (DOX) is limited by its dose-dependent cardiotoxicity. The present study investigated the effects of scutellarin against DOX-induced cardiotoxicity in rats using pharmacodynamic and pharmacokinetic approaches. DOX (20 mg/kg) was injected intraperitoneally (i.p.) as a...
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| Publicado no: | Arch Pharm Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Pharmaceutical Society of Korea
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5537312/ https://ncbi.nlm.nih.gov/pubmed/28315259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12272-017-0907-0 |
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