IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice

Recent research has shown that reparative (alternatively activated or M2) macrophages play a role in repair of damaged tissues, including the infarcted hearts. Administration of IL-4 is known to augment M2 macrophages. This translational study thus aimed to investigate whether IL-4 administration is...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Shintani, Yusuke, Ito, Tomoya, Fields, Laura, Shiraishi, Manabu, Ichihara, Yuki, Sato, Nobuhiko, Podaru, Mihai, Kainuma, Satoshi, Tanaka, Hiroyuki, Suzuki, Ken
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537273/
https://ncbi.nlm.nih.gov/pubmed/28761077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07328-z
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