lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer

One major reason for the failure of advanced colorectal cancer (CRC) treatment is the occurrence of chemoresistance to fluoropyrimidine (FU)-based chemotherapy. Long non-coding RNA HOTAIR has been considered as a pro-oncogene in multiple cancers. However, the precise functional mechanism of HOTAIR i...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Li, Peilong, Zhang, Xin, Wang, Lili, Du, Lutao, Yang, Yongmei, Liu, Tong, Li, Chen, Wang, Chuanxin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537205/
https://ncbi.nlm.nih.gov/pubmed/28918035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.07.007
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