Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies

Replication-defective (RD) recombinant simian virus 40 (SV40)-based gene delivery vectors hold a great potential for clinical applications because of their presumed non-immunogenicity and capacity to induce immune tolerance to the transgene products in humans. However, the clinical use of SV40 vecto...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Toscano, Miguel G., van der Velden, Jeroen, van der Werf, Sybrand, Odijk, Machteld, Roque, Ana, Camacho-Garcia, Rafael J., Herrera-Gomez, Irene G., Mancini, Irene, de Haan, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537168/
https://ncbi.nlm.nih.gov/pubmed/28791314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.06.007
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