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Fully Automated One-Step Synthesis of Single-Transcript TALEN Pairs Using a Biological Foundry
Transcription activator-like effector nuclease (TALEN) is a programmable genome editing tool with wide applications. Since TALENs perform cleavage of DNA as heterodimers, a pair of TALENs must be synthesized for each target genome locus. Conventionally, TALEN pairs are either expressed on separate v...
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| Publicado no: | ACS Synth Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5536959/ https://ncbi.nlm.nih.gov/pubmed/28103009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.6b00293 |
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