Retroviral expression of the human IL-2 gene in a murine T cell line results in cell growth autonomy and tumorigenicity.

In mature T lymphocytes (T cells) the regulated expression of the genes for interleukin-2 (IL-2) and its receptor (IL-2R) constitutes an essential part in controlling the cell growth. Evidence has been provided which suggests the involvement of an aberrant function of the IL-2 system in developing T...

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Bibliografiska uppgifter
Huvudupphovsmän: Yamada, G, Kitamura, Y, Sonoda, H, Harada, H, Taki, S, Mulligan, R C, Osawa, H, Diamantstein, T, Yokoyama, S, Taniguchi, T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC553693/
https://ncbi.nlm.nih.gov/pubmed/3119325
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