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Mechanisms mitigating problems associated with multiple kinetochores on one microtubule in early mitosis

Proper chromosome segregation in mitosis relies on correct kinetochore interaction with spindle microtubules. In early mitosis, each kinetochore usually interacts with the lateral side of each microtubule and is subsequently tethered at the microtubule end. However, since eukaryotic cells carry mult...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Sci
Hauptverfasser: Yue, Zuojun, Komoto, Shinya, Gierlinski, Marek, Pasquali, Debora, Kitamura, Etsushi, Tanaka, Tomoyuki U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536920/
https://ncbi.nlm.nih.gov/pubmed/28546446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.203000
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