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ARHGAP42 is activated by Src-mediated tyrosine phosphorylation to promote cell motility

The tyrosine kinase Src acts as a key regulator of cell motility by phosphorylating multiple protein substrates that control cytoskeletal and adhesion dynamics. In an earlier phosphotyrosine proteomics study, we identified a novel Rho-GTPase activating protein, now known as ARHGAP42, as a likely bio...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Luo, Weifeng, Janoštiak, Radoslav, Tolde, Ondřej, Ryzhova, Larisa M., Koudelková, Lenka, Dibus, Michal, Brábek, Jan, Hanks, Steven K., Rosel, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536916/
https://ncbi.nlm.nih.gov/pubmed/28584191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.197434
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