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Altered feto-placental vascularization, feto-placental malperfusion and fetal growth restriction in mice with Egfl7 loss of function

EGFL7 is a secreted angiogenic factor produced by embryonic endothelial cells. To understand its role in placental development, we established a novel Egfl7 knockout mouse. The mutant mice have gross defects in chorioallantoic branching morphogenesis and placental vascular patterning. Microangiograp...

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Bibliografski detalji
Izdano u:Development
Glavni autori: Lacko, Lauretta A., Hurtado, Romulo, Hinds, Samantha, Poulos, Michael G., Butler, Jason M., Stuhlmann, Heidi
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536866/
https://ncbi.nlm.nih.gov/pubmed/28526753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.147025
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