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Bone marrow adipocytes promote the regeneration of stem cells and hematopoiesis by secreting SCF
Endothelial cells and Leptin Receptor(+) (LepR(+)) stromal cells are critical sources of haematopoietic stem cell (HSC) niche factors, including Stem Cell Factor (SCF), in bone marrow. After irradiation or chemotherapy, these cells are depleted while adipocytes become abundant. We discovered that bo...
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Publicado no: | Nat Cell Biol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5536858/ https://ncbi.nlm.nih.gov/pubmed/28714970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3570 |
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