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A short amino-terminal segment of microsomal cytochrome P-450 functions both as an insertion signal and as a stop-transfer sequence.

Co-translational insertion of liver microsomal cytochrome P-450 into the endoplasmic reticulum membrane is mediated by the signal recognition particle (SRP) and the presence in the cytochrome molecule of a signal sequence that can be recognized by SRP has been postulated. To locate this signal seque...

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Vydáno v:EMBO J
Hlavní autoři: Sakaguchi, M, Mihara, K, Sato, R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553649/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2822391/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02521.x
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