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Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.

The role of tyrosine phosphorylation in the regulation of tyrosine protein kinase activity was investigated using site-directed mutagenesis to alter the structure and environment of the three tyrosine residues present in the C terminus of avian pp60c-src. Mutations that change Tyr 527 to Phe or Ser...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Reynolds, A B, Vila, J, Lansing, T J, Potts, W M, Weber, M J, Parsons, J T
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1987
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553640/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2822389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02512.x
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