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Molecular determinants for CC-chemokine recognition by a poxvirus CC-chemokine inhibitor

Poxviruses express a family of secreted proteins that bind with high affinity to chemokines and antagonize the interaction with their cognate G protein-coupled receptors (GPCRs). These viral inhibitors are novel in structure and, unlike cellular chemokine receptors, are able to specifically interact...

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Autori principali: Seet, Bruce T., Singh, Rajkumari, Paavola, Chad, Lau, Elaine K., Handel, Tracy M., McFadden, Grant
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC55364/
https://ncbi.nlm.nih.gov/pubmed/11470923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171069398
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