cAMP-dependent activation of protein kinase A attenuates respiratory syncytial virus-induced human airway epithelial barrier disruption

Airway epithelium forms a barrier to the outside world and has a crucial role in susceptibility to viral infections. Cyclic adenosine monophosphate (cAMP) is an important second messenger acting via two intracellular signaling molecules: protein kinase A (PKA) and the guanidine nucleotide exchange f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rezaee, Fariba, Harford, Terri J., Linfield, Debra T., Altawallbeh, Ghaith, Midura, Ronald J., Ivanov, Andrei I., Piedimonte, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536269/
https://ncbi.nlm.nih.gov/pubmed/28759570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181876
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