Paclitaxel-loaded and A10-3.2 aptamer-targeted poly(lactide-co-glycolic acid) nanobubbles for ultrasound imaging and therapy of prostate cancer

In the current study, we synthesized prostate cancer-targeting poly(lactide-co-glycolic acid) (PLGA) nanobubbles (NBs) modified using A10-3.2 aptamers targeted to prostate-specific membrane antigen (PSMA) and encapsulated paclitaxel (PTX). We also investigated their impact on ultrasound (US) imaging...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Wu, Meng, Wang, Ying, Wang, Yiru, Zhang, Mingbo, Luo, Yukun, Tang, Jie, Wang, Zhigang, Wang, Dong, Hao, Lan, Wang, Zhibiao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536230/
https://ncbi.nlm.nih.gov/pubmed/28794625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S136032
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