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The first step in the functional inactivation of the Escherichia coli polynucleotide phosphorylase messenger is a ribonuclease III processing at the 5' end.

The transcripts covering pnp, the gene encoding polynucleotide phosphorylase, are processed by ribonuclease III. In this study, it is shown that the steady state level of the pnp mRNA increased 11-fold in a ribonuclease III-deficient strain. The synthesis rate of this messenger is only slightly affe...

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Bibliographic Details
Published in:EMBO J
Main Authors: Portier, C, Dondon, L, Grunberg-Manago, M, Régnier, P
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3308454/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02484.x
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