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Investigating the Influence of Magnesium Ions on p53–DNA Binding Using Atomic Force Microscopy

p53 is a tumor suppressor protein that plays a significant role in apoptosis and senescence, preserving genomic stability, and preventing oncogene expression. Metal ions, such as magnesium and zinc ions, have important influences on p53–DNA interactions for stabilizing the structure of the protein a...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, Yang, Gao, Tianyong, Wang, Yanwei, Yang, Guangcan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536072/
https://ncbi.nlm.nih.gov/pubmed/28754018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071585
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