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Prediction of Protein Hotspots from Whole Protein Sequences by a Random Projection Ensemble System

Hotspot residues are important in the determination of protein-protein interactions, and they always perform specific functions in biological processes. The determination of hotspot residues is by the commonly-used method of alanine scanning mutagenesis experiments, which is always costly and time c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jiang, Jinjian, Wang, Nian, Chen, Peng, Zheng, Chunhou, Wang, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536031/
https://ncbi.nlm.nih.gov/pubmed/28718782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071543
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