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Chromatin Dynamics in Genome Stability: Roles in Suppressing Endogenous DNA Damage and Facilitating DNA Repair

Genomic DNA is compacted into chromatin through packaging with histone and non-histone proteins. Importantly, DNA accessibility is dynamically regulated to ensure genome stability. This is exemplified in the response to DNA damage where chromatin relaxation near genomic lesions serves to promote acc...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Nair, Nidhi, Shoaib, Muhammad, Sørensen, Claus Storgaard
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535976/
https://ncbi.nlm.nih.gov/pubmed/28698521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071486
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