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CD15s/CD62E Interaction Mediates the Adhesion of Non-Small Cell Lung Cancer Cells on Brain Endothelial Cells: Implications for Cerebral Metastasis

Expression of the cell adhesion molecule (CAM), Sialyl Lewis X (CD15s) correlates with cancer metastasis, while expression of E-selectin (CD62E) is stimulated by TNF-α. CD15s/CD62E interaction plays a key role in the homing process of circulating leukocytes. We investigated the heterophilic interact...

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Pubblicato in:Int J Mol Sci
Autori principali: Jassam, Samah A., Maherally, Zaynah, Smith, James R., Ashkan, Keyoumars, Roncaroli, Federico, Fillmore, Helen L., Pilkington, Geoffrey J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535965/
https://ncbi.nlm.nih.gov/pubmed/28698503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071474
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