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Biomphalaria glabrata Metallothionein: Lacking Metal Specificity of the Protein and Missing Gene Upregulation Suggest Metal Sequestration by Exchange Instead of through Selective Binding

The wild-type metallothionein (MT) of the freshwater snail Biomphalaria glabrata and a natural allelic mutant of it in which a lysine residue was replaced by an asparagine residue, were recombinantly expressed and analyzed for their metal-binding features with respect to Cd(2+), Zn(2+) and Cu(+), ap...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Niederwanger, Michael, Calatayud, Sara, Zerbe, Oliver, Atrian, Sílvia, Albalat, Ricard, Capdevila, Mercè, Palacios, Òscar, Dallinger, Reinhard
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535948/
https://ncbi.nlm.nih.gov/pubmed/28684706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071457
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