Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway

Dysfunction of the N-methyl-d-aspartate (NMDA) receptor has been implicated in the pathogenesis of schizophrenia. Although agonists for the glycine-binding sites of NMDA receptors have potential as new medication for schizophrenia, their modulation of antipsychotic-induced extrapyramidal side effect...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Shimizu, Saki, Sogabe, Shunsaku, Yanagisako, Ryoto, Inada, Akiyoshi, Yamanaka, Megumi, Iha, Higor A., Ohno, Yukihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535908/
https://ncbi.nlm.nih.gov/pubmed/28671605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071416
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