Natural RNA polymerase aptamers regulate transcription in E. coli

In search for RNA signals that modulate transcription via direct interaction with RNA polymerase (RNAP) we deep-sequenced an E. coli genomic library enriched for RNAP-binding RNAs. Many natural RNAP-binding aptamers, termed RAPs, were mapped to the genome. Over 60% of E. coli genes carry RAPs in the...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Sedlyarova, Nadezda, Rescheneder, Philipp, Magán, Andrés, Popitsch, Niko, Rziha, Natascha, Bilusic, Ivana, Epshtein, Vitaly, Zimmermann, Bob, Lybecker, Meghan, Sedlyarov, Vitaly, Schroeder, Renée, Nudler, Evgeny
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535762/
https://ncbi.nlm.nih.gov/pubmed/28648779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.05.025
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