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The conserved decanucleotide from the immunoglobulin heavy chain promoter induces a very high transcriptional activity in B-cells when introduced into an heterologous promoter.

A conserved decanucleotide (ATGCAAATNA) is present 45-60 nucleotides upstream from the transcription startpoint in all immunoglobulin heavy chain promoters (VH promoters). We have introduced this decanucleotide (cd sequence) at a similar position into the upstream flanking sequence of the mouse Reni...

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Main Authors: Dreyfus, M, Doyen, N, Rougeon, F
格式: Artigo
語言:Inglês
出版: 1987
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC553542/
https://ncbi.nlm.nih.gov/pubmed/3111845
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