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Molecular characterization of the HLA-linked steroid 21-hydroxylase B gene from an individual with congenital adrenal hyperplasia.

21-Hydroxylase deficiency which causes congenital adrenal hyperplasia is one of the most common defects of adrenal steroidogenesis. There are two 21-hydroxylase genes in man, A and B, and these have been mapped to the HLA class III region. Only the 21-hydroxylase B gene is thought to be active. To u...

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Udgivet i:EMBO J
Principais autores: Rodrigues, N R, Dunham, I, Yu, C Y, Carroll, M C, Porter, R R, Campbell, R D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553538/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3038528/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02414.x
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