Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae

Saliva of blood-feeding arthropods carries several antihemostatic compounds whose physiological role is to facilitate successful acquisition of blood. The identification of novel natural anticoagulants and the understanding of their mechanism of action may offer opportunities for designing new antit...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pirone, Luciano, Ripoll-Rozada, Jorge, Leone, Marilisa, Ronca, Raffaele, Lombardo, Fabrizio, Fiorentino, Gabriella, Andersen, John F., Pereira, Pedro José Barbosa, Arcà, Bruno, Pedone, Emilia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535037/
https://ncbi.nlm.nih.gov/pubmed/28592490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.788042
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