Adenosine A(2A) receptor inactivation alleviates early-onset cognitive dysfunction after traumatic brain injury involving an inhibition of tau hyperphosphorylation

Tau is a microtubule-associated protein, and the oligomeric and hyperphosphorylated forms of tau are increased significantly after neurotrauma and considered important factors in mediating cognitive dysfunction. Blockade of adenosine A(2A) receptors, either by caffeine or gene knockout (KO), allevia...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Zhao, Z-A, Zhao, Y, Ning, Y-L, Yang, N, Peng, Y, Li, P, Chen, X-Y, Liu, D, Wang, H, Chen, X, Bai, W, Chen, J-F, Zhou, Y-G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534966/
https://ncbi.nlm.nih.gov/pubmed/28485728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2017.98
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados