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Unravelling the regulation of insulin transport across the brain endothelial cell

AIMS/HYPOTHESIS: For circulating insulin to act on the brain it must cross the blood–brain barrier (BBB). Remarkably little is known about how circulating insulin crosses the BBB’s highly restrictive brain endothelial cells (BECs). Therefore, we examined potential mechanisms regulating BEC insulin u...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Gray, Sarah M., Aylor, Kevin W., Barrett, Eugene J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534844/
https://ncbi.nlm.nih.gov/pubmed/28601906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4285-4
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