Human Placental Hofbauer Cells Maintain an Anti-inflammatory M2 Phenotype despite the Presence of Gestational Diabetes Mellitus

BACKGROUND: Hofbauer cells (HBCs) are macrophages of the feto-placental unit. Despite the general view that these cells have an anti-inflammatory M2 phenotype, recent studies have claimed that pregnancy pathologies—e.g., gestational diabetes mellitus (GDM)—cause a switch from an M2 to an M1 pro-infl...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Schliefsteiner, Carolin, Peinhaupt, Miriam, Kopp, Susanne, Lögl, Jelena, Lang-Olip, Ingrid, Hiden, Ursula, Heinemann, Akos, Desoye, Gernot, Wadsack, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534476/
https://ncbi.nlm.nih.gov/pubmed/28824621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00888
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