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The conformations of hirudin in solution: a study using nuclear magnetic resonance, distance geometry and restrained molecular dynamics

The solution conformations of the protein hirudin have been investigated by the combined use of distance geometry and restrained molecular dynamics calculations. The basis for the structure determination comprised 359 approximate interproton distance restraints and 10 φ backbone torsion angle restra...

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Autores principales: Clore, G. Marius, Sukumaran, Dinesh K., Nilges, Michael, Zarbock, Jutta, Gronenborn, Angela M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC553426/
https://ncbi.nlm.nih.gov/pubmed/15981339
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