Poly (ADP-ribose) polymerase 1 mRNA levels strongly correlate with the prognosis of myelodysplastic syndromes

Poly (ADP-ribose) polymerase 1 (PARP-1) has a central role in the repair of DNA breaks and is a promising treatment target in malignancy. We measured PARP1 mRNA levels by a SYBR-green-based PCR in the bone marrow of 74 patients with myelodysplastic syndrome (MDS) and correlated them to their demogra...

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Publicat a:Blood Cancer J
Autors principals: Diamantopoulos, P, Zervakis, K, Zervakis, P, Sofotasiou, M, Vassilakopoulos, T, Kotsianidis, I, Symeonidis, A, Pappa, V, Galanopoulos, A, Solomou, E, Kodandreopoulou, E, Papadopoulou, V, Korkolopoulou, P, Mantzourani, M, Kyriakakis, G, Viniou, N-A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533939/
https://ncbi.nlm.nih.gov/pubmed/28212373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2016.127
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