Mapping of Transcription Termination within the S Segment of SFTS Phlebovirus Facilitated Generation of NSs Deletant Viruses

SFTS phlebovirus (SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral nonstructural protein (NSs) upon infection of cells in culture. We show that rHB29NSsKO replication...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Brennan, Benjamin, Rezelj, Veronica V., Elliott, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533932/
https://ncbi.nlm.nih.gov/pubmed/28592543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00743-17
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