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let-7 Contributes to Diabetic Retinopathy but Represses Pathological Ocular Angiogenesis

The in vivo function of microRNAs (miRs) in diabetic retinopathy (DR) and age-related macular degeneration (AMD) remains unclear. We report here that let-7 family members are expressed in retinal and choroidal endothelial cells (ECs). In ECs, overexpression of let-7 by adenovirus represses EC prolif...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Zhou, Qinbo, Frost, Robert J. A., Anderson, Chastain, Zhao, Fangkun, Ma, Jing, Yu, Bo, Wang, Shusheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533878/
https://ncbi.nlm.nih.gov/pubmed/28584193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00001-17
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