Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis

Sox2 is known to be important for neuron formation, but the precise mechanism through which it activates a neurogenic program and how this differs from its well-established function in self-renewal of stem cells remain elusive. In this study, we identified a highly conserved cyclin-dependent kinase...

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Publicat a:Mol Cell Biol
Autors principals: Lim, Shuhui, Bhinge, Akshay, Bragado Alonso, Sara, Aksoy, Irene, Aprea, Julieta, Cheok, Chit Fang, Calegari, Federico, Stanton, Lawrence W., Kaldis, Philipp
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533875/
https://ncbi.nlm.nih.gov/pubmed/28584195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00201-17
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