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Clozapine-Induced Gastrointestinal Hypomotility: A 22-Year Bi-National Pharmacovigilance Study of Serious or Fatal ‘Slow Gut’ Reactions, and Comparison with International Drug Safety Advice

INTRODUCTION: Clozapine is the preferred antipsychotic for treatment-resistant schizophrenia, but has significant adverse effects, including gastrointestinal hypomotility or ‘slow gut’, which may result in severe constipation, ileus, bowel obstruction, and even death. These gastrointestinal effects...

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Bibliografiske detaljer
Udgivet i:CNS Drugs
Main Authors: Every-Palmer, Susanna, Ellis, Pete M
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533872/
https://ncbi.nlm.nih.gov/pubmed/28623627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-017-0448-6
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