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Behaviour of intrinsically disordered proteins in protein–protein complexes with an emphasis on fuzziness

Intrinsically disordered proteins (IDPs) do not, by themselves, fold into a compact globular structure. They are extremely dynamic and flexible, and are typically involved in signalling and transduction of information through binding to other macromolecules. The reason for their existence may lie in...

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Pubblicato in:Cell Mol Life Sci
Autori principali: Olsen, Johan G., Teilum, Kaare, Kragelund, Birthe B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533869/
https://ncbi.nlm.nih.gov/pubmed/28597296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2560-7
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