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Peginterferon beta-1a reduces the evolution of MRI lesions to black holes in patients with RRMS: a post hoc analysis from the ADVANCE study

The presence of chronic black holes, i.e., chronic lesions that are hypointense on T1-weighted images and are indicative of more severe tissue injury, has been increasingly utilized as a surrogate marker of therapeutic outcome in multiple sclerosis. The ADVANCE study was a 2-year, double-blind, pivo...

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Detalhes bibliográficos
Publicado no:J Neurol
Main Authors: Arnold, Douglas L., You, Xiaojun, Castrillo-Viguera, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533848/
https://ncbi.nlm.nih.gov/pubmed/28685353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00415-017-8544-6
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