Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness

Patients with severe alcoholic hepatitis (SAH) not responding to glucocorticoid therapy have higher mortality, though they do not differ in their baseline clinical characteristics and prognostic scores from those who respond to therapy. We hypothesized that the baseline hepatic gene expression diffe...

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Vydáno v:Sci Rep
Hlavní autoři: Sharma, Shvetank, Maras, Jaswinder S., Das, Sukanta, Hussain, Shabir, Mishra, Ashwani K., Shasthry, Saggere M., Sharma, Chhagan B., Weiss, Emmanuel, Elkrief, Laure, Rautou, Pierre-Emmanuel, Gilgenkrantz, Hélène, Lotersztajn, Sophie, Paradis, Valérie, de la Grange, Pierre, Junot, Christophe, Moreau, Richard, Sarin, Shiv K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533759/
https://ncbi.nlm.nih.gov/pubmed/28754919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07161-4
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