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DDR2 controls the epithelial-mesenchymal-transition-related gene expression via c-Myb acetylation upon matrix stiffening

Increasing matrix stiffness caused by the extracellular matrix (ECM) deposition surrounding cancer cells is accompanied by epithelial–mesenchymal transition (EMT). Here, we show that expression levels of EMT marker genes along with discoidin domain receptor 2 (DDR2) can increase upon matrix stiffeni...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Daehwan, You, Eunae, Jeong, Jangho, Ko, Panseon, Kim, Jung-Woong, Rhee, Sangmyung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533734/
https://ncbi.nlm.nih.gov/pubmed/28754957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07126-7
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