KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance

Endometriosis is an inflammatory condition that is associated with progesterone resistance and cell proliferation, resulting in pain, infertility and pregnancy loss. We previously demonstrated phosphorylation of STAT3 in eutopic endometrium of infertile women with this disorder leading to over-expre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yoo, Jung-Yoon, Kim, Tae Hoon, Fazleabas, Asgerally T., Palomino, Wilder A., Ahn, Soo Hyun, Tayade, Chandrakant, Schammel, David P., Young, Steven L., Jeong, Jae-Wook, Lessey, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533722/
https://ncbi.nlm.nih.gov/pubmed/28754906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04577-w
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