Robust and accurate digital measurement for HER2 amplification in HER2 equivocal breast cancer diagnosis

Currently, there are no recommended alternative assays for HER2 cases deemed equivocal by immunohistochemistry and fluorescent in situ hybridization. Digital PCR (ddPCR), a highly accurate method to determine DNA copy number, could be a robust alternative for clinical HER2 diagnostics. HER2 and CEP1...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Wang, Yuefeng, Tsang, Julia Y. S., Cui, Yongmei, Cui, Ji, Lin, Ying, Zhao, Songli, Law, Patrick T. W., Cheung, Sai Yin, Ng, Enders K. O., Tse, Gary M. K., Ke, Zunfu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533703/
https://ncbi.nlm.nih.gov/pubmed/28754904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07176-x
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