Transfection of the int-1 mammary oncogene in cuboidal RAC mammary cell line results in morphological transformation and tumorigenicity.

The int-1 gene is often activated by proviral insertion in mouse mammary tumors. Direct evidence for the normal function of this gene and its role in tumorigenesis has therefore been lacking. To examine possible biological effects of int-1 activation in in vitro cell systems, we have constructed rec...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Rijsewijk, F, van Deemter, L, Wagenaar, E, Sonnenberg, A, Nusse, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553367/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3034569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb04729.x
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