The human cytoplasmic dynein interactome reveals novel activators of motility

In human cells, cytoplasmic dynein-1 is essential for long-distance transport of many cargos, including organelles, RNAs, proteins, and viruses, towards microtubule minus ends. To understand how a single motor achieves cargo specificity, we identified the human dynein interactome by attaching a prom...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Redwine, William B, DeSantis, Morgan E, Hollyer, Ian, Htet, Zaw Min, Tran, Phuoc Tien, Swanson, Selene K, Florens, Laurence, Washburn, Michael P, Reck-Peterson, Samara L
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2017
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533585/
https://ncbi.nlm.nih.gov/pubmed/28718761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28257
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