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Quantification of sympathetic hyperinnervation and denervation after myocardial infarction by three-dimensional assessment of the cardiac sympathetic network in cleared transparent murine hearts

BACKGROUND: The sympathetic nervous system is critical in maintaining the normal physiological function of the heart. Its dysfunction in pathological states may exacerbate the substrate for arrhythmias. Obviously, knowledge of its three-dimensional (3D) structure is important, however, it has been r...

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Veröffentlicht in:PLoS One
Hauptverfasser: Yokoyama, Teruki, Lee, Jong-Kook, Miwa, Keiko, Opthof, Tobias, Tomoyama, Satoki, Nakanishi, Hiroyuki, Yoshida, Akira, Yasui, Haruyo, Iida, Tadatsune, Miyagawa, Shigeru, Okabe, Shigeo, Sawa, Yoshiki, Sakata, Yasushi, Komuro, Issei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533449/
https://ncbi.nlm.nih.gov/pubmed/28753665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182072
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